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KMID : 0356620110260040348
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Journal of Korean Society of Endocrinology
2011 Volume.26 No. 4 p.348 ~ p.354
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A Case of Cushing’s Disease in Pregnancy
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Kim Jung-Tae
Seong Mun-Hyuk
Park Woo-Ri
Han Joung-Ho
Han Hye-Sook
Sim Young-Kwang
Oh Tae-Geun
Jeon Hwang-Gyun
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Abstract
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Developing Cushing’s syndrome during pregnancy is rare because menstruation is irregular and hypercortisolism causes infertility. Developing Cushing’s disease during pregnancy is very rare because there is even less ovulation than those with the adrenal adenoma. The clinical manifestations of Cushing’s syndrome may easily be missed during pregnancy as the features of weight gain, hypertension, and hyperglycemia overlap with those that occur during a pregnancy. Diagnosing Cushing’s syndrome during a pregnancy is complex because the biochemical features are obscured by the natural changes in the hypothalamic-pituitary-adrenal axis that occur during pregnancy. Having Cushing’s syndrome during a pregnancy results in increased fetal and maternal complications, so early diagnosis and treatment are critical. We report the clinical and endocrine findings of a pregnant women with Cushing’s disease who underwent transsphenoidal surgery after delivery.
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KEYWORD
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Cushing’s disease, Cushing’s syndrome, Pregnancy
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